The skin’s distinct structure is its fundamental role, which is to protect the body from the environment’s irritants. The skin gets made of two layers: the inner dermal layer, which assures strength and suppleness and supplies the epidermis with nutrients, and the outer epidermal layer, which is highly cellular and serves as a barrier. Vitamin C gets found in high concentrations in normal skin, where it supports several well-known and significant functions, including promoting collagen formation and aiding in antioxidant defense against UV-induced photodamage. This information gets used for adding vitamin C to topical treatments.
Vitamin C levels in normal skin are high, equivalent to those in other bodily tissues, and significantly higher than plasma, indicating active circulating accumulation. The skin’s best vitamin C serum appears in intracellular compartments, where concentrations are most likely in the millimolar range. Through the blood vessels found in the dermal layer, it enters cells. Skin vitamin C levels have not to get frequently documented, and published values vary widely, with a 10-fold range across several independent investigations.
The significant biological functions of vitamin C that are vital to skin health get indicated by the skin’s high concentration of the vitamin. The attention has been on collagen synthesis and antioxidant protection because of how vitamin C works, but there is growing evidence for other functions.
Aging can cause changes in the skin just as it might in other parts of the body. Aging produces structural and functional changes in all skin layers, which, like physiological systems, can make people more vulnerable to various disorders, such as the development of dermatoses and skin cancer. Because skin changes are the first apparent indicator of aging, they may impact our emotional and mental health.
There is very little data on a link between vitamin C levels and general skin deterioration, making it difficult to distinguish between vitamin C’s capacity to prevent additional insults brought on by excessive sun exposure, smoking, or environmental stress. The best evidence of vitamin C’s protective role in skin function comes from observations that a deficit results in overt skin issues. For instance, early indicators of scurvy include skin fragility, corkscrew hairs, and poor wound healing.
Increased consumption of the best vitamin C serum gets thought to be advantageous because a deficit impairs function. However, no research has examined the relationship between vitamin C intake or levels and aging-related alterations. Before we can enhance our understanding of what kind can be advantageous for skin health and protection against aging-related changes, vitamin C gets practically never tested in the skin.
Since it got discovered in the 1930s as a treatment for scurvy, the function of vitamin C in maintaining healthy skin has been a topic of research. The first vitamin C function closely associated with scurvy symptoms was the co-factor function for collagen hydroxylases, and the understanding of the significance of this function for skin health throughout the human lifespan led to the hypothesized vitamin C benefit for skin health.